Collagen biostimulators have become one of the most sought-after treatments in aesthetic medicine. Unlike traditional hyaluronic acid fillers that simply add volume, biostimulators activate your skin’s own natural collagen production. At Elyzea in Lima, pricing depends on the product: from S/980 (~$280 USD) per vial for Profhilo and Gouri, S/1,100 (~$315) for Sculptra, and S/3,200 (~$914) for Radiesse. In the United States, comparable products cost $800 to $1,500 per vial — the entry-level options save up to 65–81%.
If you're evaluating facial rejuvenation options, also see our breakdowns of Morpheus8 cost in Lima (microneedling with radiofrequency) and HIFU lifting — three technologies that complement biostimulators in a layered anti-aging plan.
Biostimulator Prices at Elyzea: 2026 Rates
At Elyzea, pricing varies by biostimulator. Here are the 2026 prices per vial or syringe:
- Sculptra (poly-L-lactic acid): S/1,100 per vial (~$315 USD)
- Radiesse (calcium hydroxylapatite): S/3,200 per syringe (~$914 USD)
- Profhilo (high-concentration pure hyaluronic acid): S/980 per syringe (~$280 USD)
- Gouri (liquid polycaprolactone): S/980 per syringe (~$280 USD)
Price comparison with the United States:
- Elyzea (Lima): from $280 USD per vial (Profhilo/Gouri); Sculptra $315, Radiesse $914
- United States: $800 – $1,500 USD per vial
- Savings vs. US prices: up to 65–81% on the entry-level options (Profhilo, Gouri)
What Are Collagen Biostimulators?
Biostimulators are injectable substances that stimulate your body to produce new collagen. Unlike conventional hyaluronic acid fillers — which add volume immediately but are reabsorbed within 6 to 12 months — biostimulators trigger a biological rejuvenation process that progressively and durably improves skin quality, firmness, and elasticity.
The 4 Biostimulators Available at Elyzea
Sculptra (poly-L-lactic acid)
Sculptra is the most established biostimulator on the market, originally FDA-approved under PMA P040061. It gradually stimulates type I collagen production. It’s ideal for restoring facial volume lost to aging and improving overall facial laxity. Results appear progressively over weeks and can last up to 2 years.
Radiesse (calcium hydroxylapatite)
Radiesse (manufactured by Merz Aesthetics) offers a dual effect: immediate volumetric correction (acts as a filler) and long-term collagen stimulation, per the manufacturer’s clinical information. It’s especially effective for deep nasolabial folds, hands, and redefining the facial contour. Results last 12 to 18 months.
Profhilo (pure hyaluronic acid)
Profhilo is not a conventional filler. It’s a bio-remodeler containing the highest concentration of hyaluronic acid on the market (64 mg in 2 ml). It spreads through the skin, stimulating both collagen and elastin simultaneously. It’s ideal for improving overall skin quality: deep hydration, radiance, and firmness. Results last approximately 6 to 12 months.
Gouri (liquid polycaprolactone)
Gouri is the newest biostimulator. Its liquid polycaprolactone (PCL) formula distributes evenly throughout the tissue, stimulating collagen comprehensively. Unlike other biostimulators injected at specific points, Gouri diffuses for a global rejuvenation effect. Results last up to 12 to 24 months.
For a detailed comparison between products, read our article Sculptra vs. Radiesse vs. Profhilo.
How Many Sessions Do I Need?
The number of sessions varies by product and goal:
- Typical protocol: 2 to 3 sessions spaced every 4 to 6 weeks
- Profhilo: Generally 2 initial sessions one month apart
- Sculptra: 2 to 3 sessions spaced every 6 weeks
- Progressive results: Improvement continues for weeks after each session
- Maintenance: One annual session to prolong results
Estimated investment for a 2-3 vial Profhilo or Gouri protocol: $560 to $840 USD (S/1,960 to S/2,940) — compared to $1,600 to $4,500 USD in the United States. Sculptra ($315/vial) and Radiesse ($914/syringe) are priced per product.
Biostimulators vs. Traditional Fillers
What’s the key difference?
- Fillers (hyaluronic acid): Immediate result, direct volume, duration 6–12 months. Ideal for lips, under-eyes, cheekbones
- Biostimulators: Progressive result, stimulate your own collagen, duration 1–2 years. Ideal for laxity, skin quality, global rejuvenation
- Many patients benefit from both treatments in different areas or at different times
Why Choose Elyzea in Miraflores?
- All 4 options available: Sculptra, Radiesse, Profhilo, and Gouri — Dr. Geldres recommends the best option for your specific case
- Transparent per-product pricing: from $280 USD per vial — the exact cost depends on the biostimulator, no surprises
- Medical expertise: Dr. Geldres (board-certified plastic surgeon) personally administers all biostimulators
- Complete evaluation: We determine the ideal product, number of vials, and session count before starting — virtual consultations available for international patients
- Premium location: Advanced aesthetic medicine center in Miraflores, Lima’s most walkable and visitor-friendly district