Collagen biostimulators have become one of the most sought-after treatments in aesthetic medicine. Unlike traditional hyaluronic acid fillers that simply add volume, biostimulators activate your skin’s own natural collagen production. At Elyzea in Lima, the price is $280 USD per vial (S/980) for Sculptra, Radiesse, Profhilo, and Gouri. In the United States, the same products cost $800 to $1,500 per vial — a savings of 65–81%.
If you're evaluating facial rejuvenation options, also see our breakdowns of Morpheus8 cost in Lima (microneedling with radiofrequency) and HIFU lifting — three technologies that complement biostimulators in a layered anti-aging plan.
Biostimulator Prices at Elyzea: 2026 Rates
At Elyzea, each vial or syringe of biostimulator costs S/980 (approximately $280 USD). This uniform price applies to all four options:
- Sculptra (poly-L-lactic acid): S/1,100 per vial (~$315 USD)
- Radiesse (calcium hydroxylapatite): S/980 per syringe (~$280 USD)
- Profhilo (high-concentration pure hyaluronic acid): S/980 per syringe (~$280 USD)
- Gouri (liquid polycaprolactone): S/980 per syringe (~$280 USD)
Price comparison with the United States:
- Elyzea (Lima): $280 USD per vial
- United States: $800 – $1,500 USD per vial
- Savings vs. US prices: 65–81% — a complete 3-vial protocol at Elyzea costs less than a single vial in the US
What Are Collagen Biostimulators?
Biostimulators are injectable substances that stimulate your body to produce new collagen. Unlike conventional hyaluronic acid fillers — which add volume immediately but are reabsorbed within 6 to 12 months — biostimulators trigger a biological rejuvenation process that progressively and durably improves skin quality, firmness, and elasticity.
The 4 Biostimulators Available at Elyzea
Sculptra (poly-L-lactic acid)
Sculptra is the most established biostimulator on the market, originally FDA-approved under PMA P040061. It gradually stimulates type I collagen production. It’s ideal for restoring facial volume lost to aging and improving overall facial laxity. Results appear progressively over weeks and can last up to 2 years.
Radiesse (calcium hydroxylapatite)
Radiesse (manufactured by Merz Aesthetics) offers a dual effect: immediate volumetric correction (acts as a filler) and long-term collagen stimulation, per the manufacturer’s clinical information. It’s especially effective for deep nasolabial folds, hands, and redefining the facial contour. Results last 12 to 18 months.
Profhilo (pure hyaluronic acid)
Profhilo is not a conventional filler. It’s a bio-remodeler containing the highest concentration of hyaluronic acid on the market (64 mg in 2 ml). It spreads through the skin, stimulating both collagen and elastin simultaneously. It’s ideal for improving overall skin quality: deep hydration, radiance, and firmness. Results last approximately 6 to 12 months.
Gouri (liquid polycaprolactone)
Gouri is the newest biostimulator. Its liquid polycaprolactone (PCL) formula distributes evenly throughout the tissue, stimulating collagen comprehensively. Unlike other biostimulators injected at specific points, Gouri diffuses for a global rejuvenation effect. Results last up to 12 to 24 months.
For a detailed comparison between products, read our article Sculptra vs. Radiesse vs. Profhilo.
How Many Sessions Do I Need?
The number of sessions varies by product and goal:
- Typical protocol: 2 to 3 sessions spaced every 4 to 6 weeks
- Profhilo: Generally 2 initial sessions one month apart
- Sculptra: 2 to 3 sessions spaced every 6 weeks
- Progressive results: Improvement continues for weeks after each session
- Maintenance: One annual session to prolong results
Estimated total investment for a complete protocol: $560 to $840 USD (S/1,960 to S/2,940) — compared to $1,600 to $4,500 USD in the United States.
Biostimulators vs. Traditional Fillers
What’s the key difference?
- Fillers (hyaluronic acid): Immediate result, direct volume, duration 6–12 months. Ideal for lips, under-eyes, cheekbones
- Biostimulators: Progressive result, stimulate your own collagen, duration 1–2 years. Ideal for laxity, skin quality, global rejuvenation
- Many patients benefit from both treatments in different areas or at different times
Why Choose Elyzea in Miraflores?
- All 4 options available: Sculptra, Radiesse, Profhilo, and Gouri — Dr. Geldres recommends the best option for your specific case
- Uniform pricing: $280 USD per vial for any biostimulator — no surprises
- Medical expertise: Dr. Geldres (board-certified plastic surgeon) personally administers all biostimulators
- Complete evaluation: We determine the ideal product, number of vials, and session count before starting — virtual consultations available for international patients
- Premium location: Advanced aesthetic medicine center in Miraflores, Lima’s most walkable and visitor-friendly district
Book a Free Virtual Consultation
Frequently Asked Questions about Biostimulators in Lima
What's the difference between Sculptra, Radiesse, Profhilo and Gouri?
Sculptra (poly-L-lactic acid) gradually stimulates collagen, lasts up to 2 years. Radiesse (calcium hydroxylapatite) gives immediate volume + long-term collagen, lasts 12-18 months. Profhilo is ultra-concentrated hyaluronic acid for global skin quality, lasts 6-12 months. Gouri (liquid polycaprolactone) diffuses for whole-face rejuvenation, lasts 12-24 months.
How many sessions do I need?
Typical protocol is 2-3 sessions spaced 4-6 weeks apart. Profhilo usually requires 2 initial sessions one month apart. Sculptra is administered in 2-3 sessions every 6 weeks. Improvement continues for weeks after each session.
When will I see results?
Results are progressive. First improvements are noticeable at 4-6 weeks (skin quality, hydration). Full result peaks at 3-6 months once the stimulated collagen has fully formed. Unlike hyaluronic acid filler, there's no immediate 'before and after.'
How long do results last?
Sculptra lasts up to 24 months, Radiesse 12-18 months, Gouri 12-24 months, Profhilo 6-12 months. All benefit from an annual maintenance session.
Do biostimulator injections hurt?
Topical anesthesia is applied, and for Sculptra and Radiesse, products are usually mixed with lidocaine to reduce discomfort. Most patients describe mild discomfort. The session lasts 30-45 minutes.
How do I choose the right biostimulator?
It depends on the goal. For facial structure and progressive volume: Sculptra. For jawline contour or deep folds: Radiesse. For global skin quality without adding volume: Profhilo. For natural global rejuvenation: Gouri. The free consultation determines which fits your case.
Are biostimulators reversible?
Not entirely. Profhilo is hyaluronic acid, so it's dissolvable with hyaluronidase. But Sculptra, Radiesse, and Gouri are not dissolvable — the effect dilutes with the natural product degradation timeline. That's why an experienced physician injector is critical.
Biostimulators or hyaluronic acid — which is better?
They're complementary, not exclusive. Hyaluronic acid (S/850/syringe) gives immediate volume and lasts 9-18 months. Biostimulators stimulate your own collagen and last 1-2 years. Many patients combine: biostimulators for global structure, HA for specific definition.
Why does the injector matter?
More than with any other injectable. Since they're not easily reversible, biostimulators require deep knowledge of facial vascular anatomy. Sculptra's post-injection massage technique is critical to avoid nodules. Dr. Geldres — a board-certified plastic surgeon — personally administers all biostimulators.
How much do I save vs the United States?
At Elyzea, the complete 2-3 vial protocol costs S/1,960-S/2,940 (~US$560-840). In the US, the same protocol costs US$1,600-4,500. Average savings: 65-81%.
Fillers at Elyzea — product selection and placement matters
The visible difference between great filler results and disappointing ones is rarely the brand of product — it is the product selected for the specific anatomical zone and the placement technique. Hyaluronic acid fillers (Juvederm, Restylane, Belotero) come in different densities calibrated for different layers (deep cheek vs lip vs tear trough). Calcium hydroxylapatite (Radiesse) and poly-L-lactic acid (Sculptra) are biostimulators with different durability and biological response profiles. The right product for the right placement is what produces natural, anatomically appropriate results. At Elyzea, Dra. Geldres is a board-certified plastic surgeon with detailed knowledge of facial anatomy and the product behavior of each filler family — and she will recommend the product that fits your specific concern, not "the filler we have on hand."
Why Elyzea is different in Lima
Three things separate Elyzea from most aesthetic-medicine providers operating in Lima and across Latin America. First, we use real, manufacturer-genuine equipment — not the Chinese imitations sold under similar-sounding brand names that flood the regional market. Whether the procedure involves a HIFU platform, a CO₂ laser, a Morpheus8 unit, a picosecond laser, or any other technology, the device is the genuine FDA-cleared (or equivalent) product, with manufacturer service contracts and original consumables. Second, an MD anesthesiologist is on-site for procedures that require it. Topical numbing alone is inadequate for many protocols at the depth or energy that actually delivers results; on-site anesthesia means we can run the protocol as designed without forcing patients to grit through pain or quietly reducing energy mid-procedure. Third, a full clinical setup includes a treatment room, an anesthesia bay with proper emergency equipment, a private recovery room where patients can decompress 30–60 minutes before leaving, and a dispensary that stocks post-procedure care products. Not a single-bed spa room.
For patients flying to Lima from the US, Canada, Europe, or other Latin American countries, this clinical infrastructure is the prerequisite — not a marketing add-on. When you're a medical tourist, you don't have a local primary-care doctor and you don't have family in the same time zone. The clinic itself has to be capable of handling whatever happens during and after the procedure, in real time.